I believe biomedia is mostly misunderstood.
The media touted as best, has millions of pores for BB can live in.
But if media is full of gunk, or pores are slathered in layers of old bio-film, then anything within those pores is in a dead zone. BB need aerobic conditions and contact with flow to use the ammonia and nitrate, if water is sliding over bio-film, this is compromized. If a canister is not cleaned regularly it loses efficiency. I believe that not cleaning canisters often is not a good idea, and because they are difficult to clean in comparison to other filters, they usually are usually not.
I don't see being under pressure, having to mess around with large O rings, and worrying air lock preventing start of flow as being user friendly.
Maybe the new models are better, and less troublesome, but I gave up on canisters years ago for all the above reasons, and it would take a lot of data to the contrary to do so.