I've only found limited studies on the osmotic regulation proerties of fully aquatic frogs. These studies indicate that the use of CO2 in closed aquarium systems can cause asphyxiation to the frogs when the levels of CO2 displace O2 in closed-top aquarium. Such as when the lights are off. Plants absorb oxygen and give off CO2 in the absence of light. Couple this with a CO2 generator running on the system and conditions can now exist where there isn't enough oxygen for the frogs to breath.
maybe if you aerate at night (assuming this is for a planted tank, otherwise wtf are you adding co2 for?) most aquatic frogs can also breathe air so if you provide some open surface area that may help...
There's only one species of aquatic frog that doesn't breath air (that I know of). It lives in Lake Titicaca in Peru (Telmatobius culeus). And, with the lake being the highest in elevation (over 12,500ft), this frog is also the only amphibian known to survive at these altitudes. The frog's skin is covered with capillary-filled skin extensions that exchange O2 and CO2 (cutaneous respiration).
maybe if you aerate at night (assuming this is for a planted tank, otherwise wtf are you adding co2 for?) most aquatic frogs can also breathe air so if you provide some open surface area that may help...