For a big tank consider the big filters
for canisters thats FX5, The largest of the Eheims or a pressurized pond filter (such as the BioForce 2000)
 
Do yourself a favor and never set up a filter for bio only
Having mechanical filtration prior to the bio media prevents waste from collecting in the bio media. This means you have to clean the bio media far less often. Whenever you clean bio media you will remove some bacteria, thus preventing the need to clean it will be greatly to your advantage. Also physical waste will clog fine pores in ceramic type bio media which reduces surface area and cuts existing bacteria off from the system resulting in a bacteria loss (potential mini cycle).