Delgado, that is not quite right.
The internal saline levels of both fresh and salt water fish are pretty much identical. the osmatic regulation they go through is to keep them that way. The SW fish have a lower salt content than the water around them, and vice versa for the fresh water fish, but that is in comparison to the water they are in, not to each other.
Some parasites and diseases can be transfered between SW and FW environments but they are not common at all.
Some cyprinids do contain high levels of thiaminase and can cause thiamin defficiencies but that is true when fed as a large percentage of the diet to freshwater fish as well.
I have not kept any large SW fish but have often used live sardines and herring as feeders for FW fish and have never had a problem doing so.