Running undissolved gas through most filters and pumps can cause vapor lock or otherwise damage them. Wat back when I ran pressurized CO2 I needed to be able to make a filter double as a "diffuser." The idea was the impeller would chop the bubble enough for it it to be sufficiently dissolved by the time the water was returned to the tank. So I saw my challenge as being one of finding a canister filter that could withstand this.
My conclusion was I would only attempt it with and Eheim canister and I used their relatively new Pro 2 2026. I can say the following about the system.
1. The tank was a 50 gal., but the layout reduced the water volume by at least 1/3.
2. It normally ran 24/7 at 1 bps. The co2 line was inserted into the intake via the prefilter. The spraybar was submerged and i never saw any gas coming out of it.
3. I ran the set-up for just under 10 years when I sold the CO2 system and repurposed the tank.
4. There was no plant I could not grow as long as it did not get really tall.
5. I set this up in late 2002 and had it going by early 2003. I still have the canister today running. It has pretty much been running continuously since 2003.
6. I lost almost no fish in this tank and, despite being a community set-up, my farlowellas spawned in it.
I cannot say this would work in a much larger tank. My best guess is the challenge would be more one of dispersing the dissolved CO2 all over the tank where it is needed. I would assume it might make more sense to have the CO2 laden water being returned in a few different places in the tank. I leave it to those who have done co2 in big tanks before to confirm this or not.