Yea that was kinda broad. I guess first I was asking if they would breed together even with the size difference and second yeah if they would do fine with larger cichlids.
I was too anxious to wait for answers and I went ahead and put the tiny female into my 150 with the 4" male. After just a couple of minutes they found each other and the male almost immediately started dancing and brought her over to 'his' flowerpot. Not sure if they would really make a good couple yet, because I've seen her get chased around by other cichlids when she strays away from the flowerpot and the male hasn't been very protective of her and doesn't seem to care unless it happens near 'his' flowerpot. But I have my fingers crossed, it would be cool to have them breed in a cichlid community type tank.
BTW in the same tank I also have: 6" oscar that I had just rescued, 6" green sev, 5" giant gourami, 3" rd, 5" nicaraguensis, 5" delhezi bichir, 10" ropefish, 6" rb pacu. Most of these fish were given to me or I had rescued them from craigslist and I do not plan on keeping them all together in there forever.