I would go with 4x AquaClear 110. They are cheap and easy maintanence. Remove the carbon, and replace all 4 with an extra bag of BioMax ceramic media.
If you want to hastle with Canister filters, they can be more effecient at times.
Undergravel filters are effecient, but can be a timebomb in the making. They also don't have a great aesthetic appeal.
Bio-Wheel filters are great, but for a heavy bio-load, I dont think it can host enough beneficial bacteria on the wheels alone. You could also modify these and make them more effecient by adding ceramic bio-media.
A wet-dry and a sump are likely the most effecient for a high bio-load. If you do not keep good maintenance on the wet-dry, they can be a ticking time bomb just like unmaintained canister filters and undergravel filters. If you add a sump, it will help because you are increasing gallonage. However, you will still have to add a method of filtration within the sump, and maintain it as well..
Good Luck!
Don't forget, combining any of these methods can be effecient as well! Just remember to keep your filtration systems clean
Miles