The only problem is when you look at turnover of 5 x's you see that 125 x 5 = 625 so one would assume that 1 ac110 at I think 900 gallons an hour would be more than enough but that would not be the case. Your canister would be more for bio and the ac110 as an actual filter for the most part but what the 2 together would do is leave no dead spots;as long as you have them on separate sides of the tank. When you add air to the mix it also helps with water movement as well.Or you could also get a power head to move water. As nutcase said, you don't want dead spots.
You also have to be reasonable with how much fish is in the tank...more fish= more turnover needed etc.