Hello everyone, I am reaching out for help because I am at a standstill with my Firemouth's Hole in the Head. This condition has existed for a couple years and has got steadily worse with time. I could not do much with treating him as I was not home that often. He used to accept multiple foods, but really only eats the Hikari Carnivore pellets. To my knowledge, the 75g he was in for years had 0 ammonia, but recently discovered ammonia was .25. I remember randomly testing the 75g's water throughout the years, and there was no ammonia. Nevertheless, there was no NO2 or excessively high NO3. I believe NO3 was around 40-60ppm. I am aware NO3 should be 20ppm or less ideally and I do feel bad about that. I feel comfortable in saying that the PH was 7.4-7.6. I have tried medications throughout the years and nothing has helped. It was just until recently I put the Firemouth in my 20g hospital tank again with the following water parameters: 0 NH3, 0 NO2, 20 N03, 7.4 PH. The lesions that were once holes have only got worse and new holes have developed. I did three treatments of API General Cure with no luck. I also did one or two treatments of API Furan 2 with no luck. I did two treatments of API Tetracyline possibly three or four months ago with no luck. Currently, I have taken him off the antibiotics and am combining API Melafix with Pimafix. I threw API Stress Coat in as well throughout any treatment. I have an airstone going and the temperature is at 80 degrees Fahrenheit. I will try to get some pictures soon. He has not eaten in two weeks and I understand getting Metro into the GI Tract is more effective than Metro being in the water. I did test the GH and am not remembering the specific number, but the result was higher than the middle number for that scale. He will only eat in the 75g and I am thinking about putting him back temporarily to get some nutrients into his system and starting treatment again in the 20g hospital tank.