Your loach may not even have worms.
Skinny disease is often caused from internal parasites, typically spironucleus, not nematodes.
If your fish are still eating then treating for internal parasites such as spironucleus is relatively easy. See following link for more details.
http://www.monsterfishkeepers.com/forums/showthread.php?523470-Treating-Hexamita-aka-Spironucleus
As far as worms, PraziPro aka Praziquantel is an is an anthelmintic cestodicide which is basically only effective at treating tapeworms, flatworms, & flukes. It contains <5% praziquantel by weight, and is designed specifically to be used as a dewormer, not to treat internal (or external) parasites such as flagellates, flukes, etc.
For nematodes (round worms) you're better off treating with levamisole as per the directions in the following link.
https://edis.ifas.ufl.edu/fa091
The author of that paper linked to above, Dr. Roy Yanong, is an Associate Professor and Extension Veterinarian, Program in Fisheries and Aquatic Sciences, University of Florida, Tropical Aquaculture Laboratory.
An excellent read on Levamisole, how it works, and how to effectively use it to treat round worms was previously linked to by MilitantPotato -
http://www.loaches.com/Members/shari2/levamisole-hydrochloride-1/talkback/1185808900/document_view
Personally I would start with an anti-parasitic treatment, then follow up with a deworming agent if that doesn't correct the problem.