I have thought about trying this before, but some fishkeepers say that it does not work well in a freshwater setup. Although there was one guy that told me that it worked well for his tank. The problem seems to be that the protein skimmer works better in a saltwater setup because the water can be chopped into finer bubbles than freshwater. I guess if you could modify the pump so that it can produce smaller bubbles it might work in a freshwater setup. I would get a pieace of enkamat and put it on the propeller and see if it produces real tiny bubbles and see if it makes a difference. I might just set mine up and give it a try and see if it does or does not work. I still think that if a skimmer works for a salt water setup it can work for a freshwater setup too.
Btw, protein skimmers (depending on brand) can take anywhere between 1-2 weeks to "break in" and start pulling crap out of the water. In the mean time you will probably have to tweak the skimmer to get the skimmer at the proper water level in the mixing chamber and the collecting cup. Sometimes instead of skimming all the skimmer does is pull water to the collecting cup, like I said you will need to make constant adjustments to make sure you get it working right.