F1 hybrids is a term used in genetics and selective breeding. F1 stands for Filial 1, the first filial generation seeds/plants or animal offspring resulting from a cross mating of distinctly different parental types. The offspring of distinctly different parental types produce a new, uniform variety with specific and/or desirable characteristics from either or both parents. In fish breeding, those parents frequently are two closely related fish species, while in plant and animal genetics those parents usually are two inbred lines. Mules are F1 hybrids between horse and donkey. Crossing specific parent plants produces a hybrid seed (plant) by means of controlled pollination. To produce consistent F1 hybrids, the original cross must be repeated each season. As in the original cross, in plants this is usually done through controlled hand-pollination, and explains why F1 seeds can often be expensive. F1 hybrids can also occur naturally, a prime example being peppermint, which is not a species evolved by cladogenesis or gradual change from a single ancestor, but a sterile stereotyped hybrid of watermint and spearmint. Unable to produce seeds, it propogates through the vining spread of its own root system.