If you want them to breed again, right away. They're very good parents, and won't go back into the rhythmn of things until they're gone... Unless they don't. Then they eat their young to clear the room for the next batch-in-the-making. Mine haven't. They've just happily all swam together for forever... ok - 6 months. And the fry are half the size of mom and dad, and still no sign that parenting has taken a back seat to mating (and I have enough that it wouldn't be a problem if they did!). So the bottom line is that it's a crap shoot. But the soon you pull the fry away the more you're guaranteed to have because there is the risk that ma and pa will get hungry. It also make a difference how experienced they are. It took me three batches for one set of jewels to produce a viable "clutch" (ok, not the right word. sue me), a different set twice, and both now actively produce lots. My convicts got it right from the get-go. Moving the fry too soon (aout two weeks) from my favorite set caused them to go into fear mode and shift from being king/queen of the tank to being never-to-be-seen-again critters -- which they never were before. So decide how important the fry are to you and make your decision. Fish are individuals and there's practically no absolute rule (skip the chlorine. That's a good one to keep in mind) so you're on your own with your best judgement. Grab the ball and run with it.