I agree end products of thiosulfate and chlorine will accumulate in tank, if always adding more thiosulfate and chlorine with each water change! However, what precisely are these end products and should we worry about them?
Na2S2O3 + 5 H20 + 4 Cl2 ---> 2 Na+ + 2 SO4-- + 10 H+ + 4 Cl-
So, we see that all end products are harmless and very commonly occurring.
I think such small quantity of sodium ions and chloride ions take long, long, long, long time, if ever, before tank water become brackish! Also, if fish still growing bigger, they very good st storing sodium (and chloride) ions inside their bodies.
Sulfate ions are also harmless. If anything, they can precipitate heavy metal toxins out of water, so may actually be good thing.
However, note hydrogen ions produced, which make water acidic. Some buffering capacity in tank water, therefore, should be good idea.
Hope I help,
Kuji out.