I got the 303b and it has 3 layers/baskets. The flow goes down the UV tube first and then works its way back up through the media baskets. The way I ran mine was to put the mechanical sponge on the bottom of the lowest basket and then filled the rest of that basket with the included bio balls. The next basket up I filled with ceramic rings (I got the media package also and the amount of ceramic rings it came with was not nearly enough, so I added a ton more that I have on hand for my large build). Then, in the top/last basket I put the three water polishing pads. This has worked great and the water has never been as clear as it is now.
If you have 4 baskets, and you got the media package that includes the bio balls, I would recommend you get enough sponges to fill up the bottom basket. Then, fill the second basket with the bio balls. Next, fill the third basket up with ceramic rings. Lastly, fill the top basket with water polishing pads.
If you want to start from scratch with adding media, I would recommend starting off with filling the bottom/first basket with sponge(s). Then, fill both of the middle baskets with ceramic rings. Lastly, fill the top/last basket with filter floss.
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