I just got an idea... you know those "flowing" Christmas lights? What if you put those up in there above the glass (take out the existing bulb(s)), then put a colored gel (colored transparent plastic sheet) underneath? I bet if you used a really dark blue or red gel, you could get some SWEET lighting effects! Maybe even use some of the cardboard like you guys previously mentioned to get that cutout/dark spot effects!
MAN! Now I want to go out and make one!