I would consult with the builder of the home. Other than that, you will have to check the floorboards and supports under the floor and then run some calculations on the weight/per sq ft that the floor can handle. Unfortunately, unless somebody else here is living in the same home and can tell you it worked for them, there is really no way somebody is going to be able to tell you if it will work or not.
I think you are at a pretty safe with your weight estimate. The 150 gallons of water (I know it won't be quite an entire 150 gallons but we want to be careful so lets assume more weight rather than less) weighs about 1251lb. Then, the weight of the tank itself, the stand and the equipment will probably put you near the 1800lb mark. This is assuming you are not using a sump. If you are using a sump then you will need to factor in the weight of the extra water that is contained in the sump.
What you will have to do it find out how much weight the floor will hold per sq ft and then take the weight of your setup and divide it by the sq feet its footprint takes up. If the capacity of the floor is greater than the weight per sq ft of your setup then you are good, if it's vice versa then it's a no go.
Example: Your floor can hold 200lbs per sq ft. Your tank has a footprint of 6ftx2ft and weighs 1800lbs. Your footprint area is 6x2=12sq ft. Take the 1800lbs and divide it by 12sq ft. This will give you 1800/12=150lbs per square foot. This is well within the capacity of the floor and would be fine. If it were any closer then I would say it is safer to not try it because boards and supports are not all perfect.