Will Prime or Safe Reduce the effectiveness of medication if added?

[Rocksor]

So can I add Safe/Prime to neutralize the ammonia excreted by the fish in a medicated tank rather than do a large water change everyday to remove the ammonia? I want to know if it is possible so that I don't have to do a 75% water change everyday and then re-dose the tank with the medication. I'm treating the QT with Furan-2 if that makes a difference.

How long can I add Prime/Safe before a water change is inevitable, when the ammonia reaches 2.0ppm?

 

[Aquanero]

IDK as a precaution I wate a half hour after adding before adding meds. This isn't based on anything it just makes me feel better. Maybe someone will come by that knows for sure.

 

[Rocksor]

The answer that Seachem gave me is that there are no issues with using Safe/Prime with erythromycin, kanamycin, tetracycline, or nitrofurazone. The only medications that they do not recommend using with Safe/Prime are copper based medications. It will turn copper into a more toxic form.