Yes but follow his schedule. Here’s the instructions from his website:
“ USE: Add 1 packet to each 125 NET Gallons. Very concentrated and strong, so often one treatment is needed. Can be safely doubled, especially with coldwater fish.
Treat again in 3 days if needed (after 20%+ water change)
If combined with AAP Kanamycin, still treat only once while treating with Kanamycin every other day and re-treat with AAP Yellow Powder after 3 days if needed.
Can be combined with the superior AAP Yellow Powder (premium nitrofurazone) (or the lower quality Furan 2) & Metronidazole for parasitic, fungal, & bacterial infections.
IN FACT, for Columnaris or difficult cases of Aeromonas, this combinations is often a MUST as combined these two medications form a symbiotic bond that is not completely understood, but what is known is used alone, these two are often ineffective for Columnaris.”
