I just did this and completely screwed my cycle!!
I removed 80% of the water, enough so I could drag the tank to where i wanted it, then i put enough prime in for a triple dose on my size tank (600L) then i refilled the tank, after about 2 hours my water went like milk, my ammonia test was through the roof and my cycle was destroyed!
PRIME DOES NOT WORK FAST ENOUGH TO SUPPORT LARGE WATER CHANGE!!!
If i was you i would try and get a drum and keep your existing tank water, OR dis connect your existing filter, or turn it off, app prime, refill the tank, add use a powerhead to mix the water for at least 1-2 hours!! then reconnect your filter!
I do 80% water changes all the time with Prime with no issue. Does your water have chloramine in it? Was this after a heavy rain or around a seasonal change?
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