I use sumps, with about 20 different tanks, on many different tiers (levels), with about 5 or more tanks per sump.
I find although canisters to do a good job at sequestering detritus, and making a tank appear to be clean (clear), that often masks the real degraded water quality issue of the sequestered (swept under the rug, yet still in the tank) detritus sitting in uncleaned cans, so unless that detritus is regularly purged from the can, produces high nitrate, clear water, yet chemically saturated.
To me the accessibility of a sump for maintenance far out weighs the non-user friendliness of cans.
I also often don't always put sumps right under tank, they can be off set, or even in another room, on a lower floor, in a closet or even in a basement to avoid water movement noise.
I also like the many more filtration options (restricted only by ones imagination) offered when using sumps.
An example in the pic below.
An off set sump, with a 4ft tall biological/fractionation unit in it, all heaters, filter socks and other unsightly gear in the sump away from display tank view, yet totally open to ease in maintenance.
