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The Magdalena basin contains many endemic fishes, most notably Eremophilus (Trichomycteridae), Genycharax (Characidae), Carlastyanax (Characidae), and Centrochir (Doradidae), which are endemic genera to the basin. Ichthyoelephas is another local genus, restricted to this ecoregion and the North Andean Pacific Slopes - Rio Atrato ecoregion [301]. The unique characid genus Grundulus is found in the upper Magdalena around the savanna of Bogota, whereas the monotypic Dupouyichthys sapito (Aspredinidae) is only shared with the Maracaibo basin. Several genera have assemblages of endemic species in the basin, including Apteronotus, Astroblepus, Brycon, Bryconamericus, Chaetostoma, Creagrutus, and Hemybrycon. Cynopotamus magdalenae and Acestrocephalus anomalus (Characidae), Pseudopimelodus schultzi (Pseudopimelodidae), Xyliphius magdalenae (Aspredinidae), Eremophilus mutisii (Trichomycteridae), and Creagrutus caucanus and C. brevipinnis (Characidae) are endemic to the upper Río Cauca; C. magdalenae is endemic to the Río Magdalena; and C. nigrostigmatus is only known from Caño Pechilín, a small coastal stream west of the mouth of the Magdalena (Harold & Vari 1994).
Other noteworthy fishes
Mountain stream fishes (astroblepids, trichomycterids, loricariids, characids) live in Andean uplands and mountains. This ecoregion shares some species (e.g., characids Creagrutus affinis and Roeboides dayi) with river systems in the westerly adjacent North Andean Pacific Coasts - Río Atrato ecoregion [301], and others (e.g., characid Gilbertolus alatus, ctenoluciid Ctenolucius hujeta, and pimelodid Sorubim cuspicaudus) with the easterly adjacent Maracaibo ecoregion [303] (Harold and Vari 1994; Vari 1995; Menezes and Lucena 1998; Littmann et al. 2000; Lucena 2000).