Refrain from using chemicals. Water changes are your better option. Believe it or not, most chemicals do not work efficiently. Doing more water changes eliminates ammonia, nitrite and nitrate in the process. Please get API liquid test kit and test for those three variables. Bigspizz is correct. We need those water parameters.
If your filter is producing vigorous surface movements, oxygen is not an issue. This is ammonia and nitrite intoxication. Only water changes can correct that. With that size of stock list, I would be doing 4 times water changes in a week by at least 40-50%.