That is the thread I started a while back, Dr Joe.
And in theory aquaventions, the more salt and hardness, the better.
But one of my tanks, which is brackish (3+ ppt salinity), the skimmer is less effective than on a totally fresh water tank. I believe it may have more to do with the water pressure exertedby the pump on the venturi valve, and the amount of fish in the tank.
Even though it doesn't always foam though, doesn't mean it isn't working.
i have done tests in the lab with turbidity and checked waste efluent from the skimmer under the microscope.
The population of microbes in the waste is always @ triple, that of straight tank water. And suspended solid waste is at least triple, when desicated and weighed.
I believe it can also be considered an extra aeration device, and at the same time, has the ability to help remove saturated microbubbles that occur in water from the tap here in WI in winter that can be dangerous to fish, due to the cold weather.
I hope I don't sound like I'm trying to make fractionation into a panacea, I also believe in frequent partial water changes, planted sumps for nitrate removal and I use filter socks for particulate. Fractionation is just another addition to the arsenal.