I used the Seaclone 100 for about 2 years on a 55 gallon reef tank with no problems. About 2 years ago I put it on a 125 gallon reef tank and had no problems. My friend also uses one in his wet/dry filter under his 125 gallon reef tank and he has had no problems.
I don't have any salt tanks set up at the moment but I maintained several of them a few years ago. I used a pair of Seaclones and moved them from tank to tank to prevent over skimming. (weekly servace.) They worked great and never gave me any headaches.