I would do it. I will be running an fx5 and 3 ac110's on my 125 when it all arrives thanks to tax returns with the fx5 it allows you to load it with bio material.
Believe it or not, I was only running AC110s on it. Weekly water tests were fine, but I still performed a 50% water change. I noticed that after adding a few extra fish that my levels changed dramatically. I now perform a 70% water change 2 times a week. The first FX5 will be here on Tuesday. That will give me a bit more clarity, but I'm thinking 2 FX5s with 2 AC110s would make my life much easier.
Thinking of two FX5's even before you have hooked up one is definately overkill. A bigger tank could be better tham more filtration in your situation especially if your fish are going to need a larger home.
One line of thought that lends weight to the bigger is better idea is that with more water comes more buffering from water changes. A 180g with an FX5 and 2 ac110s should keep your parameters in check especially with your water changing regime.