I've kept a few captive-bred and wild-caught red bloods. The wild-caught ones were back in the old days, when they had the worst rep, and they were nothing but trouble. Years ago a good friend of mine's wife had one strike upwards at her from a bucket and got her in the face - luckily the wounds weren't anywhere near as bad as they could have been. These were vile-tempered pythons for sure!
Now on the other hand, the captive-bred ones I've had have been total pussycats - great feeders, very mellow, big and beautiful as only bloods can be, etc...and I've always kept them as I would any of other pythons, however, like reticulated pythons, bloods can have trouble at shedding time if you don't watch the humidity or give them a good soaking...apart from that I find them to be little trouble at all...
Cheers!
Simon