It sounds like the power wire has a short to ground. Check around wwhere it goes through the firewall, into the trunk, or anywhere the wire could be pinched or chafed. A bad ground is possible, but dosent explain the blown fuses. Check ohms between the negative terminal on the amp and a known good ground on the car. There should be zero (or VERY close to it)ohms. If you have a reading over .1, then you have a bad ground. Check ohms between the power wire to the amp and a known good ground (you should disconnect the wire from the amp first). You should have infinate ohms (no connection). If there is less than infinate ohms, you have a short to ground in the power wire. Also, check that your ground location is actually part of the main body of the car (I usually use a seatbelt bolt). Another thing...a system draws a lot of power. You prbably added somewhere between an 8 to 4 guage wire to the positive side of the battery. In order for the electrons to flow at the maximum rate, you need to add a same size wire to the negative side, too. It's the one in, one out rule. Run it between the negative terminal on the battery and a known good ground on the body under the hood. Keep this wire as short as possible.