Siphon some in a bucket then use a colander and agitate the bio media with your hands in the tank water. Works for me and has worked since 95fsirico;2682167; said:but with bio balls it would be hard to clean a little at a time. you will always be taking the top layer to be cleaned and the bottom will never be cleaned. you would have to take all the bio balls out i think. if your tank is not overloaded do you think the gravel would have bacteria to keep the tank going. if you use your tank water bio balls should make a quick rebound as long as they don't dry out wright?