If you don't do discus, how would you feel about a large African setup?
You could do a large planted Congo River Tank, and stock heavily with small-medium sized fish. Upper jaw polys like ornates, sens, dels, and some groups of ropefish would be cool to see grow to full size. Various pairs/small groups of cichlids (Steatocranus, Congochromis, Haplochromis, Orthochromis, Pelvicachromis, Nanochromis, kribs, etc). Large tetra schools (congo tetra, long-finned tetra, african moon tetra, yellow-tailed tetra, etc). Small shoals of Distochodus (sixbar, silver, etc). Various groups of Synodontis (angelicus, decorus, nigriventris, eupterus, etc). Freshwater butterflyfish, ctenopomas, and elephant nose fish could round off the collection. You could tie in a tank for a fahaka, cross river, or a congo pufferfish, or some african snakeheads if you're outside of the USA.
Or you could do a Nile-themed tank. You could keep a group of Foskhalii tigerfish as the main swimming fish, perhaps along with a big African arowana or two, and a small group of odoe pikes. A few giraffe catfish could swim along the bottom, and you could have some bichirs in there as well - Laps, or even PBBs if your wallet is feeling it.
Just some thoughts
Drew