Sorry to hear about your pleco...now I have complete picture as to your inquiry about other plecos 

Sorry to hear about your pleco...now I have complete picture as to your inquiry about other plecos![]()
Ironically, for the very reason that reducing agents such as Seachem Prime and Safe will begin reducing 02 levels the moment the chlorine/chloramine has been reduced, Seachem has recently lowered their recommended dosage rate across the board. There is a VERY real risk of 02 depletion when using their products, and I have seen the results first hand in local tanks. Some very nice, expensive, dead fish.
Nice fem
Does it apply only to Prime and Safe, not sodium thiosulfate. My tap water is chlorinated only. I would say I overdose several times over the necessary dosage each time I do fin level WC as my tap water is nearly void of chlorine by the time it comes off the tap. I have never observed oxygen depletion as the cascading water will only aerate to oxygen saturation point.