No, and the HLLE link imo isn't from the dust likely.. but more so it removes both good and bad things from the water ( ie minerals and vitamins) as it's also been linked to a poor diet... made a few lightbulbs go there.. lol. But no like others I use it only when needed to remove meds or when I'm concerned about my water quality ( being on a well in spring when everything thaws I get abit worried if the fish start acting odd and add it for peace of mind) Carbon or its ilk Purigen aren't used in my tanks as regular parts of maintenece, but are useful tools when needed.