I know lions can tigers and hybridize, forming a liger. Yes, ligers are real, search for them on youtube. But I'm not sure if it is possible to hybridize a lion or tiger with a house cat. I doubt it. It could be, and the result would be very cool, but even artificially inseminating a cat with lion semen or the reverse wouldn't guarantee offspring. Their DNA could be to different for it to work. But again, I have no idea. And if it did work, the hybrids would probably display a range of color and shape from both sets of genes, so of a litter of five, 2 could be the size of house cats with tiger stripes, two could be the size of tigers with house cat appearance, and one could be halfway in between in terms of size and color/appearance.