A wet/dry filter is going to be your BEST means of moving large quantities of water and providing a good means of biological filtration. Wet/dry's are not the great mechanical filters so I would go with Lunk's suggestion of a wet/dry and a FX5. I am currently making a 40 gallon long tank into a wet/dry filter for my 220 and it will have a Fluval FX5 canister on it also.
Basically with a wet/dry your limiting factor is the intake, if your tank isn't pre-drilled then you can either have it drilled and install overflows or you have to use overflow boxes and depending on how many GPH they're rated at, that can limit how much water movement you can get through the filter. I am going to use a Mag-18 for my wet/dry, at 0 head it flows around 1800 gph, I think it'll be somwhere around 4' of head so I'm guessing I'll get at least 1200gph and with the FX5 being rated at 925 gph, I'll be right around 2000gph through my 220, which is right where I want to be.