suprised this thread is still around, i treated with full dosage of each maracyn product, which cured most of the columnaris, the last few days of treatment i used kannaplex, and my fish came back to life quickly, eyes cleared right up and ulcers fell off the skin, both fish were extremely weak though at this point with constant doses of medication and no appetite for a full month, unfortunately my fish were finally cured and during final tank cleaning to remove all meds from the water i left the guard of my powerhead and after coming home from purchasing some food for them, my powerhead was the one well fed, one of the gulpers was lodged in the intake, and unfortunatly did not survive, the other one went on to survive but i sold a few months back as i didnt want to use a 55 for one fish and couldnt afford a few more gulpers