I have treated popeye several times before .... most of the time successfully. I presently have a Rotkeil Severum male that, out of the blue, developed the popeye condition in both eyes. If one eye pops, it has been said that it could be injury-caused, with both eyes, bacterial infection most likely. My treatment uses two medications, kamamycin (kanaplex) to combat any bacterial infection (gram negative, most likely) and metronidazole to treat any spironucleus present. I quarantined the fish in a 10G aquarium, with quite heavy aeration (air stone, no filtration) and have added two TBSP of Epsom salts per the 10G to draw excess fluids from the fish. After about 5 days, the swelling has significantly reduced in both eyes and some puss and fluids are being released from around the edge of the eyes. I have started feeding small amounts of food which he is taking readily. Now, keep in mind that this is what I've done with reasonably good success. It may or may not work for you. Popeye can be tricky. I have added medications every second day, according to the instructions on the containers and after a roughly 30% water change. Hope you are able to save your FH.
