The true cause of HITH is debated, the organism that activelly involve is a protozoa called Hexamita that is very common as a low grade intestinal infection of cichlid and other fish, much like E. coli bacteria live in humans. The sensory pits on the fish get irritated and the tissue lining them starts to break down, It might be due to long term nitrate exposure, dietary imbalance, reduce resistance to disease, high bacterial loads, whatever. Then the damaged tissue is colonisee bt the protozoal who eat the damaged tissue and release digestive enzymes that damage more tissue allowing the infection to spread.
A human analogy is take a human, lock them in a room and feed them junk food while also giving them inadequete means to stay clean. Then when they start to get pimples and boils expose them to a staph bacteria in their wash water. Then watch the pimples turn into jungle ulcers. Sort of like that.
The meds, mainly metronidazol, used for HITH are anti-parasitical rather than antibiotic.
A human analogy is take a human, lock them in a room and feed them junk food while also giving them inadequete means to stay clean. Then when they start to get pimples and boils expose them to a staph bacteria in their wash water. Then watch the pimples turn into jungle ulcers. Sort of like that.
The meds, mainly metronidazol, used for HITH are anti-parasitical rather than antibiotic.