The majority of BB live in the filter or on rocks, sand, glass etc, not free floating in the water column. Therefore you would lose very little do to the use of UV.
As for UV on canister filters, they usually have so much flow that it is hard to imagine they are in contact with the algae long enough to kill it. Parasites require even longer exposure. This is why standalone units only have a flow of about 50 GPH.
To answer your original question I use 2 filters, one setup for mechanical with plenty of fibre media to catch particles and one with strictly bio media. Both are large enough to filter the tank by themselves, at least on paper.