The only way that one can truly know how much Prime (or whatever) to add to their tank is by knowing what quantity of chlorine or chloramine is being added by their local water treatment facility, or more importantly, what the rate is as it leaves the facility for end use.
Without that data, treating your water becomes purely hit or miss.
There are a lot of things one has to factor in before they can say with certainty "how much" water conditioner each tank requires, starting by knowing whether you have chlorine, or chloramine treated tap water, and how much of either (in mg/l) you are treating for. Seachem Prime states 1 capful per 50 gallons, but that's for 4 mg/l chloramine, and/or 5 mg/l chlorine. In my case I can safely use half that amount, as I'm only treating for 2 mg/l chloramine. (the max found in our local water supply)