Geneticists speak about a phenomenon of "Hybrid Vigour". This is when the offspring of two genetically distinct parents sometimes proves more robust than either of its parents. This may apply to resistance to disease, or better adaptation to environmental conditions such as temperature change or oxygen levels etc.
This effect was utilized to produce a sport fish species in North America called a 'Splake'. These are hybrids of Lake Trout and Speckled Trout. Both species are not that far down the branch on the evoltionary tree from one another but distinct enough to produce mule offspringe when crossed. Splake are faster growing and more tolerant of poorer water qualities than either parent species. As mules they are unable to reproduce and must be continually produced in hatcheries for release into the wild and the waiting anglers who prize them for their fight and their taste.
In the case where more closely related species are crossed and produce viable progeny, hybrid vigour is still observed. In sexual reproduction the inherited genetetic code of a parent is shuffled much like cutting a deck of cards a couple of times before producing sperm and ova to produce the next generation. So, F-1 offspring inherit 'chunks of their grandparents DNA, 25% from each grandparent. In the case of hybrid vigour the F-1 generation inherits intact 'packets' of genes that produce characteristics that make the hybrid stronger or more beautiful. They inherit the advantages that both parent species have to offer.
The problem ocours at the F-2 cross. When the genetic material is 'cut' again, many of the favourable gene combinations that produce the vigorous characteritics are lost, and the resulting offspring are less able to withstand environmental stresses than either generation before. We need to be mindfull of creating hybrids as quite often later generations become more fragile..or butt ugly.
Selective breeding within a species or natural selection produces more stable results than hybridization. The only problem is that it takes too long for some eager breeders.
Either way breeding fish is an exciting and rewarding aspect of the hobby. My personal opinion on hybrids is each to his own-just don't release fish in to the wild...