Safety is it's main advantage. It's stronger as well, but much more expensive.
I would phrase it differently. When I grew up, we didn't have seat belts, shoulder harnesses, or air bags, yet we felt relatively safe. We
were relatively safe. But many people felt it wasn't safe enough. It wasn't a white and black question, it was a relative one.
A tank with a 2.5 safety factor might be safe, but it isn't going to be as safe, all other things being equal, as a tank with a 3.8 safety factor. I think you can find people who have built tanks with 2.5 safety factors (in this forum perhaps) and those tanks are fine. However, there is a real and measurable difference between a 2.5 and a 3.8 safety factor. E.g., the amount of deflection the glass has will differ. The lower you go, the more likely you are to see a failure.
"Buildings commonly use a factor of safety of 2.0 for each structural member. The value for buildings is relatively low because the loads are well understood and most structures are redundant. Pressure vessels use 3.5 to 4.0, automobiles use 3.0, and aircraft and spacecraft use 1.2 to 3.0 depending on the application and materials. Ductile, metallic materials tend to use the lower value while brittle materials use the higher values." https://en.wikipedia.org/wiki/Factor_of_safety
Glass is a brittle material.
https://en.wikipedia.org/wiki/Brittleness