Plec and Rope fish.

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Yes, keeping plecos (especially the common types such as your hypostomus/plecostomus) with polypterids is a risky choice. They are notorious for sucking on the bodys of polypterids, and causing skin infections that could lead to death.
I have two Rope fish in with the Pleco, about 5 years with out incident. I think his mouth is to big. LOL
 
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