I'm still not understanding how a wooden box could change size IF you epoxy all exposed surfaces inside and out. Humidity could only cause expansion if it can reach the wood. If the box "expands" you'd still have change of support or pressure issues to deal with if you use glass or a similar liner. You'd want something completely flexible.
Covering all wooden parts with epoxy might fix the humidity level inside the wood. I didn't considered that option, as the glass-liner idea, was to avoid working with epoxy in the first place (which i am not familiar/comfortable with).
When the wooden box expands it still offers flat surfaces that will perfectly support the glass liners. Only the elastic silicone rubber sealing in all corners, will sqeeze/stretch. The glass moves freely together with the plywood boards (I assume).
In response to nzafi, i like the liquid rubber / pond amour as it adresses the issues with wood/humidity. But the junction to the frontglass will not be as straight forward as silikone wont adhere.
I plan to start constructing during the winter season, and for now I lean towards giving the glass/wood approach a shot. This week a have a meeting with a danish guy who has got experiance with both plywood and glass-only diy for big setups.
Thanks for all your great input. Greatly appreciated