I've got three in my 125g. Two are set to 79 and they tag-team it. The third is set to around 76 is more of a life preserver, a "just in case" heater.
The rest of my tanks only have one heater now. I've learned through accidents that fish really aren't fazed by a temperature drop when well-fed and in good water. My 55g heater died and the tank crashed from 80 down to 60 degrees in about ten hours as I frantically tried to come up with a free heater and ended up taking the debt and buying one new. Anyway, the angelfish, jurupari, giant otto and other supposedly sensitive fish didn't even seem to notice. And I just met a guy breeding bushy-nose plecos in an outdoor shed at about 70 without a problem. I strongly suspect we overheat our fish most of the time. And that an occasional catastrophic temperature crash is something a healthy fish should have no problem enduring. So it's one heater per tank from now on for me.