I use a 55 for my 220. I have baffles to divide it into three chambers.
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First chamber holds some sponge/filter floss and ceramic rings for bio. (I plan on doing away with the filter floss and replacing with several layers of poret foam)
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Next chamber is the refugium area and also holds the heaters. I plan on putting red cherry shrimp in here.
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Last chamber is the pump chamber.
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I run a herbie style overflow for silence and turn over about 1600gph currently. My overflows consist of two 1.5" full siphon overflows (with each ball valve closed about half way) and a third dry 1.5" overflow as the e-drain.
Full siphon
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Full siphon
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E-drain
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Ball valves on all drains
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With my new adjustable Jebao DCP pumps, keeping the siphon going is easy and the sump is completely quiet.
I also use and InkBird heater controller to control the two heaters. It's extremely easy to use, gets great reviews on SimplyDiscus (the 308, not the 306) and is about $35 on Amazon.
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I pretty much used all vinyl tubing.
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If you have questions about anything specific, let me know. I can definitely get pictures of anything in my setup you want a closer look at.
What size tank are you setting up and what size sump?