it's probabaly some sort of fungus ,put him your quarantine tank when you're done cycling it and put in acidophilus tablets (unscrew the capsule and tip the powder into the tank)
if your pleco eats some, don't worry it's not toxic its natural fungus eating good bacteria,the water will be cloudy for a while but it does clear up,i've tried it once. My tank had lots of mess in it oscars are messy eaters and i have an oscar. after a couple of days the uneaten food started growing white fungus on it! so i took a good bacteria tablet (acidophillus) and put the powder in the tank after a couple more days, the good bacteria had eaten 95% of all the fungus (my oscar was completely fine,he even ate some acidophillus as an added bonus) but it sure took care of the problem, a water change later the remaining 5% of fungus was gone! The acidophillus should kill the fungus growing on your pleco's fin but it won't make the parts of the fin that the fungus has destroyed grow back, so you'll have to wait a while before your pleco's fin grows back, but your pleco won't be in any danger after the fungus is gone but that's the main thing, right?