the more water changes you do, in my experience, the happier and healthier your fish will be. my best results happen with 2 50% water changes every day. so about 75% new water daily.
Do you have to do so much? no. will you notice a difference with 50% a day. probably not. will you notice a difference from 50% a week, maybe.
as long as you aren't stressing your fish with different water parameters, new water is better than old.
Whatever neccessary to keep the nitrates less than 10ppm for me, usually. If i have to skip a week, then I don't sweat it too bad.