Can lymphocystis be confused with any other diseases?
Yes. In early stages of the disease, the nodules may be relatively small and may be confused with the parasites Ichthyophthirius multifiliis (Ich, freshwater white spot disease), Cryptocaryon irritans (marine white spot disease), digenean trematodes ("grubs"), or heavy infection with Epistylis (a stalked, ciliated, protistan parasite). Lymphocystis nodules may also be confused with epitheliocystis (an intracellular bacterial disease), clumps of fungus, or mucus tags. Some skin neoplasias (cancers) may also be confused with lymphocystis.
Because of the potential confusion with other disease agents, diagnosis of lymphocystis should be accomplished by a qualified fish health professional to rule out these other potential causes.