When i cut or machine plastics or acrylics i spray the saw or bit with silicone usually food grade bought at grainger or mcmasterr carr. I think it lubricares better then water.
A carbide-tipped blade with a lot of teeth will make a pretty clean cut. To avoid chipping adjust the blade height/depth so it is only a little bit higher/deeper than the thickness of the acrylic you're cutting, and cut slowly and steadily.
A rough saw count is bad for acrylic, you will most likely end up with pieces flying everywhere. Get a plywood blade (high tooth count) for a table saw.