If you had been a regular with your cleaning of your substrate, and have more bio media than is required by your tanks conditions, then NO changing substrate should not have any noticeable effect on your water parameters.
If you were not regular with substrate cleaning, have insufficient / inefficient bio filtration, then potentially YES, you could have water parameter issues.
If you were not regular with substrate cleaning, have insufficient / inefficient bio filtration, then potentially YES, you could have water parameter issues.
